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Autophagy mediates astrocyte death during zinc potentiated ischemia reperfusion injury

Pathological release of excess zinc ions and the resultant increase in intracellular zinc has been implicated in ischemic brain cell death, although the underlying mechanisms are not fully understood. Since zinc promotes the formation of the autophagic signal, reactive oxygen species (ROS), and incr...

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Dettagli Bibliografici
Pubblicato in:Biol Trace Elem Res
Autori principali: Pan, Rong, Timmins, Graham S., Liu, Wenlan, Liu, Ke Jian
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4470843/
https://ncbi.nlm.nih.gov/pubmed/25758719
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12011-015-0287-6
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