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Autophagy mediates astrocyte death during zinc potentiated ischemia reperfusion injury

Pathological release of excess zinc ions and the resultant increase in intracellular zinc has been implicated in ischemic brain cell death, although the underlying mechanisms are not fully understood. Since zinc promotes the formation of the autophagic signal, reactive oxygen species (ROS), and incr...

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Detalhes bibliográficos
Publicado no:Biol Trace Elem Res
Main Authors: Pan, Rong, Timmins, Graham S., Liu, Wenlan, Liu, Ke Jian
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4470843/
https://ncbi.nlm.nih.gov/pubmed/25758719
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12011-015-0287-6
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