The Receptor for Advanced Glycation End Products (RAGE) Enhances Autophagy and Neutrophil Extracellular Traps in Pancreatic Cancer

Neutrophil extracellular traps (NETs) are formed when neutrophils expel their DNA, histones and intracellular proteins into the extracellular space or circulation. NET formation is dependent on autophagy and is mediated by citrullination of histones to allow for unwinding and subsequent expulsion of...

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Publicat a:Cancer Gene Ther
Autors principals: Boone, Brian A., Orlichenko, Lidiya, Schapiro, Nicole E., Loughran, Patricia, Gianfrate, Gianmarino C., Ellis, Jarrod T., Singhi, Aatur D., Kang, Rui, Tang, Daolin, Lotze, Michael T., Zeh, Herbert J.
Format: Artigo
Idioma:Inglês
Publicat: 2015
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4470814/
https://ncbi.nlm.nih.gov/pubmed/25908451
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cgt.2015.21
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