The Effects of GPX-1 Knockout on Membrane Transport and Intracellular Homeostasis in the Lens

Glutathione peroxidase-1 (GPX-1) is an enzyme that protects the lens against H(2)O(2)-mediated oxidative damage. The purpose of the present study was to determine the effects of GPX-1 knockout (KO) on lens transport and intracellular homeostasis. To investigate these lenses we used (1) whole lens im...

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Pubblicato in:J Membr Biol
Autori principali: Wang, Huan, Gao, Junyuan, Sun, Xiurong, Martinez-Wittinghan, Francisco J., Li, Leping, Varadaraj, Kulandaiappan, Farrell, Melissa, Reddy, Venkat N., White, Thomas W., Mathias, Richard T.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2008
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4470390/
https://ncbi.nlm.nih.gov/pubmed/19067024
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00232-008-9141-5
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