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Mathematical modelling of the automated FADU assay for the quantification of DNA strand breaks and their repair in human peripheral mononuclear blood cells

BACKGROUND: Cells continuously undergo DNA damage from exogenous agents like irradiation or genotoxic chemicals or from endogenous radicals produced by normal cellular metabolic activities. DNA strand breaks are one of the most common genotoxic lesions and they can also arise as intermediates of DNA...

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Detalhes bibliográficos
Publicado no:BMC Biophys
Main Authors: Junk, Michael, Salzwedel, Judy, Sindlinger, Thilo, Bürkle, Alexander, Moreno-Villanueva, Maria
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4470348/
https://ncbi.nlm.nih.gov/pubmed/26085926
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13628-014-0009-z
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