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Clinical Results of Hypomethylating Agents in AML Treatment

Epigenetic changes play an important role in the development of acute myeloid leukemia (AML). Unlike gene mutations, epigenetic changes are potentially reversible, which makes them attractive for therapeutic intervention. Agents that affect epigenetics are the DNA methyltransferase inhibitors, azaci...

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Detalhes bibliográficos
Publicado no:J Clin Med
Main Authors: Cruijsen, Marjan, Lübbert, Michael, Wijermans, Pierre, Huls, Gerwin
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4470235/
https://ncbi.nlm.nih.gov/pubmed/26237015
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/jcm4010001
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