PLGA-Loaded Gold-Nanoparticles Precipitated with Quercetin Downregulate HDAC-Akt Activities Controlling Proliferation and Activate p53-ROS Crosstalk to Induce Apoptosis in Hepatocarcinoma Cells

Controlled release of medications remains the most convenient way to deliver drugs. In this study, we precipitated gold nanoparticles with quercetin. We loaded gold-quercetin into poly(DL-lactide-co-glycolide) nanoparticles (NQ) and tested the biological activity of NQ on HepG2 hepatocarcinoma cells...

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Publicado en:Mol Cells
Autores principales: Bishayee, Kausik, Khuda-Bukhsh, Anisur Rahman, Huh, Sung-Oh
Formato: Artigo
Lenguaje:Inglês
Publicado: Korean Society for Molecular and Cellular Biology 2015
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4469909/
https://ncbi.nlm.nih.gov/pubmed/25947292
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.14348/molcells.2015.2339
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