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PLGA-Loaded Gold-Nanoparticles Precipitated with Quercetin Downregulate HDAC-Akt Activities Controlling Proliferation and Activate p53-ROS Crosstalk to Induce Apoptosis in Hepatocarcinoma Cells

Controlled release of medications remains the most convenient way to deliver drugs. In this study, we precipitated gold nanoparticles with quercetin. We loaded gold-quercetin into poly(DL-lactide-co-glycolide) nanoparticles (NQ) and tested the biological activity of NQ on HepG2 hepatocarcinoma cells...

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Dades bibliogràfiques
Publicat a:Mol Cells
Autors principals: Bishayee, Kausik, Khuda-Bukhsh, Anisur Rahman, Huh, Sung-Oh
Format: Artigo
Idioma:Inglês
Publicat: Korean Society for Molecular and Cellular Biology 2015
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4469909/
https://ncbi.nlm.nih.gov/pubmed/25947292
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.14348/molcells.2015.2339
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