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PC-PLC/sphingomyelin synthase activity plays a central role in the development of myogenic tone in murine resistance arteries

Myogenic tone is an intrinsic property of the vasculature that contributes to blood pressure control and tissue perfusion. Earlier investigations assigned a key role in myogenic tone to phospholipase C (PLC) and its products, inositol 1,4,5-trisphosphate (IP(3)) and diacylglycerol (DAG). Here, we us...

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Detalhes bibliográficos
Publicado no:Am J Physiol Heart Circ Physiol
Main Authors: Mauban, Joseph R. H., Zacharia, Joseph, Fairfax, Seth, Wier, Withrow Gil
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4469871/
https://ncbi.nlm.nih.gov/pubmed/25888510
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00594.2014
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