Decreased melatonin secretion is associated with increased intestinal permeability and marker of endotoxemia in alcoholics

Chronic heavy alcohol use is known to cause gut leakiness and alcoholic liver disease (ALD), but only 30% of heavy drinkers develop increased intestinal permeability and ALD. The hypothesis of this study was that disruption of circadian rhythms is a potential risk factor in actively drinking alcohol...

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Vydáno v:Am J Physiol Gastrointest Liver Physiol
Hlavní autoři: Swanson, Garth R., Gorenz, Annika, Shaikh, Maliha, Desai, Vishal, Forsyth, Christopher, Fogg, Louis, Burgess, Helen J., Keshavarzian, Ali
Médium: Artigo
Jazyk:Inglês
Vydáno: American Physiological Society 2015
Témata:
Mucosal Biology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4469868/
https://ncbi.nlm.nih.gov/pubmed/25907689
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpgi.00002.2015
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