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Decreased melatonin secretion is associated with increased intestinal permeability and marker of endotoxemia in alcoholics

Chronic heavy alcohol use is known to cause gut leakiness and alcoholic liver disease (ALD), but only 30% of heavy drinkers develop increased intestinal permeability and ALD. The hypothesis of this study was that disruption of circadian rhythms is a potential risk factor in actively drinking alcohol...

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Publicat a:Am J Physiol Gastrointest Liver Physiol
Autors principals: Swanson, Garth R., Gorenz, Annika, Shaikh, Maliha, Desai, Vishal, Forsyth, Christopher, Fogg, Louis, Burgess, Helen J., Keshavarzian, Ali
Format: Artigo
Idioma:Inglês
Publicat: American Physiological Society 2015
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4469868/
https://ncbi.nlm.nih.gov/pubmed/25907689
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpgi.00002.2015
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