Association of histone acetylation at the ACTA2 promoter region with epithelial mesenchymal transition of lens epithelial cells

PURPOSE: Epithelial mesenchymal transition (EMT) plays a central role in the development of fibrotic complications of the lens. The current study is designed to check whether EMT of lens epithelial cells (LECs) is regulated by epigenetic modifications and to evaluate the effect of Trichostatin-A (TS...

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Dades bibliogràfiques
Publicat a:Eye (Lond)
Autors principals: Ganatra, D A, Rajkumar, S, Patel, A R, Gajjar, D U, Johar, K, Arora, A I, Kayastha, F B, Vasavada, A R
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2015
Matèries:
Laboratory Study
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4469664/
https://ncbi.nlm.nih.gov/pubmed/25853442
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/eye.2015.29
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