Monocytes Activate Natural Killer Cells via Inflammasome-induced Interleukin 18 in Response to Hepatitis C Virus Replication

BACKGROUND & AIMS: Production of interferon (IFN)γ by natural killer (NK) cells is attenuated during chronic infection with the hepatitis C virus (HCV). We investigated whether this is due to intrinsic or extrinsic mechanisms of NK cells. METHODS: Peripheral blood mononuclear cells (PBMC) were c...

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Detalhes bibliográficos
Publicado no:Gastroenterology
Main Authors: Serti, Elisavet, Werner, Jens M., Chattergoon, Michael, Cox, Andrea L., Lohmann, Volker, Rehermann, Barbara
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4469643/
https://ncbi.nlm.nih.gov/pubmed/24685721
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1053/j.gastro.2014.03.046
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