The effects of parenteral amino acid therapy on protein carbamylation in maintenance hemodialysis patients

OBJECTIVE: Protein carbamylation is a urea-driven post-translational protein modification associated with mortality in dialysis patients. Free amino-acids (AAs) are competitive inhibitors of protein carbamylation and animal studies suggest increasing AA concentrations reduces carbamylation burden. W...

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Detalhes bibliográficos
Publicado no:J Ren Nutr
Main Authors: Kalim, Sahir, Ortiz, Guillermo, Trottier, Caitlin A., Deferio, Joseph J., Karumanchi, S. Ananth, Thadhani, Ravi I., Berg, Anders H.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4469570/
https://ncbi.nlm.nih.gov/pubmed/25753604
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1053/j.jrn.2015.01.019
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