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Polymerase ε (POLE) ultra-mutated tumors induce robust tumor-specific CD4+ T cell responses in endometrial cancer patients
OBJECTIVE: Around 7–10% of endometrial carcinomas are characterized by Polymerase-ε-(POLE) exonuclease-domain-mutations, an ultra-mutated-phenotype and a favorable prognosis. It is currently unknown whether POLE ultra-mutated-tumors are more immunogenic when compared to the other groups of endometri...
שמור ב:
| הוצא לאור ב: | Gynecol Oncol |
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| Main Authors: | , , , , , , , , , , , , , , |
| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
2015
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4469551/ https://ncbi.nlm.nih.gov/pubmed/25931171 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ygyno.2015.04.027 |
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