Generation and characterization of a SIVmac239 clone corrected at four suboptimal nucleotides

BACKGROUND: SIVmac239 is a commonly used virus in non-human primate models of HIV transmission and pathogenesis. Previous studies identified four suboptimal nucleotides in the SIVmac239 genome, which putatively inhibit its replicative capacity. Since all four suboptimal changes revert to the optimal...

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Vydáno v:Retrovirology
Hlavní autoři: Fennessey, Christine M, Reid, Carolyn, Lipkey, Leslie, Newman, Laura, Oswald, Kelli, Piatak, Michael, Roser, James D, Chertova, Elena, Smedley, Jeremy, Gregory Alvord, W., Del Prete, Gregory Q, Estes, Jacob D, Lifson, Jeffrey D, Keele, Brandon F
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2015
Témata:
Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4469405/
https://ncbi.nlm.nih.gov/pubmed/26076651
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12977-015-0175-3
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