Generation and characterization of a SIVmac239 clone corrected at four suboptimal nucleotides

BACKGROUND: SIVmac239 is a commonly used virus in non-human primate models of HIV transmission and pathogenesis. Previous studies identified four suboptimal nucleotides in the SIVmac239 genome, which putatively inhibit its replicative capacity. Since all four suboptimal changes revert to the optimal...

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Bibliographische Detailangaben
Veröffentlicht in:Retrovirology
Hauptverfasser: Fennessey, Christine M, Reid, Carolyn, Lipkey, Leslie, Newman, Laura, Oswald, Kelli, Piatak, Michael, Roser, James D, Chertova, Elena, Smedley, Jeremy, Gregory Alvord, W., Del Prete, Gregory Q, Estes, Jacob D, Lifson, Jeffrey D, Keele, Brandon F
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2015
Schlagworte:
Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4469405/
https://ncbi.nlm.nih.gov/pubmed/26076651
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12977-015-0175-3
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