The siRNA cocktail targeting interleukin 10 receptor and transforming growth factor-β receptor on dendritic cells potentiates tumour antigen-specific CD8(+) T cell immunity

Dendritic cells (DCs) are promising therapeutic agents in the field of cancer immunotherapy due to their intrinsic immune-priming capacity. The potency of DCs, however, is readily attenuated immediately after their administration in patients as tumours and various immune cells, including DCs, produc...

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Salvato in:
Dettagli Bibliografici
Pubblicato in:Clin Exp Immunol
Autori principali: Ahn, Y-H, Hong, S-O, Kim, J H, Noh, K H, Song, K-H, Lee, Y-H, Jeon, J-H, Kim, D-W, Seo, J H, Kim, T W
Natura: Artigo
Lingua:Inglês
Pubblicazione: BlackWell Publishing Ltd 2015
Soggetti:
Translational
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4469167/
https://ncbi.nlm.nih.gov/pubmed/25753156
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cei.12620
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