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Revealing the Mechanisms of Protein Disorder and N-Glycosylation in CD44-Hyaluronan Binding Using Molecular Simulation

The extracellular N-terminal hyaluronan binding domain (HABD) of CD44 is a small globular domain that confers hyaluronan (HA) binding functionality to this large transmembrane glycoprotein. When recombinantly expressed by itself, HABD exists as a globular water-soluble protein that retains the capac...

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Bibliografski detalji
Izdano u:Front Immunol
Glavni autor: Guvench, Olgun
Format: Artigo
Jezik:Inglês
Izdano: Frontiers Media S.A. 2015
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4468915/
https://ncbi.nlm.nih.gov/pubmed/26136744
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2015.00305
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