Autophagy Inhibitors as a Potential Antiamoebic Treatment for Acanthamoeba Keratitis

Acanthamoeba cysts are resistant to extreme physical and chemical conditions. Autophagy is an essential pathway for encystation of Acanthamoeba cells. To evaluate the possibility of an autophagic Acanthamoeba encystation mechanism, we evaluated autophagy inhibitors, such as 3-methyladenine (3MA), LY...

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Bibliographic Details
Published in:Antimicrob Agents Chemother
Main Authors: Moon, Eun-Kyung, Kim, So-Hee, Hong, Yeonchul, Chung, Dong-Il, Goo, Youn-Kyoung, Kong, Hyun-Hee
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2015
Subjects:
Clinical Therapeutics
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4468686/
https://ncbi.nlm.nih.gov/pubmed/25896709
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.05165-14
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