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Autophagy Inhibitors as a Potential Antiamoebic Treatment for Acanthamoeba Keratitis

Acanthamoeba cysts are resistant to extreme physical and chemical conditions. Autophagy is an essential pathway for encystation of Acanthamoeba cells. To evaluate the possibility of an autophagic Acanthamoeba encystation mechanism, we evaluated autophagy inhibitors, such as 3-methyladenine (3MA), LY...

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Publicat a:Antimicrob Agents Chemother
Autors principals: Moon, Eun-Kyung, Kim, So-Hee, Hong, Yeonchul, Chung, Dong-Il, Goo, Youn-Kyoung, Kong, Hyun-Hee
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2015
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4468686/
https://ncbi.nlm.nih.gov/pubmed/25896709
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.05165-14
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