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Autophagy Inhibitors as a Potential Antiamoebic Treatment for Acanthamoeba Keratitis

Acanthamoeba cysts are resistant to extreme physical and chemical conditions. Autophagy is an essential pathway for encystation of Acanthamoeba cells. To evaluate the possibility of an autophagic Acanthamoeba encystation mechanism, we evaluated autophagy inhibitors, such as 3-methyladenine (3MA), LY...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Main Authors: Moon, Eun-Kyung, Kim, So-Hee, Hong, Yeonchul, Chung, Dong-Il, Goo, Youn-Kyoung, Kong, Hyun-Hee
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4468686/
https://ncbi.nlm.nih.gov/pubmed/25896709
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.05165-14
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