Enterococcus faecalis Gelatinase Mediates Intestinal Permeability via Protease-Activated Receptor 2

Microbial protease-mediated disruption of the intestinal epithelium is a potential mechanism whereby a dysbiotic enteric microbiota can lead to disease. This mechanism was investigated using the colitogenic, protease-secreting enteric microbe Enterococcus faecalis. Caco-2 and T-84 epithelial cell mo...

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Detalhes bibliográficos
Publicado no:Infect Immun
Main Authors: Maharshak, Nitsan, Huh, Eun Young, Paiboonrungruang, Chorlada, Shanahan, Michael, Thurlow, Lance, Herzog, Jeremy, Djukic, Zorka, Orlando, Roy, Pawlinski, Rafal, Ellermann, Melissa, Borst, Luke, Patel, Siten, Dotan, Iris, Sartor, Ryan B., Carroll, Ian M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2015
Assuntos:
Cellular Microbiology: Pathogen-Host Cell Molecular Interactions
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4468563/
https://ncbi.nlm.nih.gov/pubmed/25916983
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00425-15
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