A Neutralizing Monoclonal IgG1 Antibody of Platelet-Activating Factor Acetylhydrolase SsE Protects Mice against Lethal Subcutaneous Group A Streptococcus Infection

Group A Streptococcus (GAS) can cause life-threatening invasive infections, including necrotizing fasciitis. There are no effective treatments for severe invasive GAS infections. The platelet-activating factor (PAF) acetylhydrolase SsE produced by GAS is required for invasive GAS to evade innate imm...

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Vydáno v:Infect Immun
Hlavní autoři: Liu, Mengyao, Feng, Wenchao, Zhu, Hui, Lei, Benfang
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2015
Témata:
Molecular Pathogenesis
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4468528/
https://ncbi.nlm.nih.gov/pubmed/25916987
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00073-15
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