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Novel Aggregation Properties of Candida albicans Secreted Aspartyl Proteinase Sap6 Mediate Virulence in Oral Candidiasis

Candida albicans, a commensal fungus of the oral microbiome, causes oral candidiasis in humans with localized or systemic immune deficiencies. Secreted aspartic proteinases (Saps) are a family of 10 related proteases and are virulence factors due to their proteolytic activity, as well as their roles...

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Détails bibliographiques
Publié dans:Infect Immun
Auteurs principaux: Kumar, Rohitashw, Saraswat, Darpan, Tati, Swetha, Edgerton, Mira
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology 2015
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4468525/
https://ncbi.nlm.nih.gov/pubmed/25870228
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00282-15
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