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Immunogenic Display of Purified Chemically Cross-Linked HIV-1 Spikes
HIV-1 envelope glycoprotein (Env) spikes are prime vaccine candidates, at least in principle, but suffer from instability, molecular heterogeneity and a low copy number on virions. We anticipated that chemical cross-linking of HIV-1 would allow purification and molecular characterization of trimeric...
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| Vydáno v: | J Virol |
|---|---|
| Hlavní autoři: | , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
American Society for Microbiology
2015
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4468504/ https://ncbi.nlm.nih.gov/pubmed/25878116 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.03738-14 |
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