Stable Phenotypic Changes of the Host T Cells Are Essential to the Long-Term Stability of Latent HIV-1 Infection

The extreme stability of the latent HIV-1 reservoir in the CD4(+) memory T cell population prevents viral eradication with current antiretroviral therapy. It has been demonstrated that homeostatic T cell proliferation and clonal expansion of latently infected T cells due to viral integration into sp...

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Bibliografiske detaljer
Udgivet i:J Virol
Main Authors: Seu, Lillian, Sabbaj, Steffanie, Duverger, Alexandra, Wagner, Frederic, Anderson, Joshua C., Davies, Elizabeth, Wolschendorf, Frank, Willey, Christopher D., Saag, Michael S., Goepfert, Paul, Kutsch, Olaf
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2015
Fag:
Virus-Cell Interactions
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4468477/
https://ncbi.nlm.nih.gov/pubmed/25878110
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00571-15
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