Extensive proteomic and transcriptomic changes quench the TCR/CD3 activation signal of latently HIV-1 infected T cells

The biomolecular mechanisms controlling latent HIV-1 infection, despite their importance for the development of a cure for HIV-1 infection, are only partially understood. For example, ex vivo studies have recently shown that T cell activation only triggered HIV-1 reactivation in a fraction of the la...

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Veröffentlicht in:PLoS Pathog
Hauptverfasser: Carlin, Eric, Greer, Braxton, Lowman, Kelsey, Duverger, Alexandra, Wagner, Frederic, Moylan, David, Dalecki, Alexander, Samuel, Shekwonya, Perez, Mildred, Sabbaj, Steffanie, Kutsch, Olaf
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2021
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7846126/
https://ncbi.nlm.nih.gov/pubmed/33465149
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1008748
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