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AID/APOBEC deaminases and cancer

Mutations are the basis for evolution and the development of genetic diseases. Especially in cancer, somatic mutations in oncogenes and tumor suppressor genes alongside the occurrence of passenger mutations have been observed by recent deep-sequencing approaches. While mutations have long been consi...

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Pubblicato in:Oncoscience
Autori principali: Rebhandl, Stefan, Huemer, Michael, Greil, Richard, Geisberger, Roland
Natura: Artigo
Lingua:Inglês
Pubblicazione: Impact Journals LLC 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4468319/
https://ncbi.nlm.nih.gov/pubmed/26097867
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