Betadoublet: de novo design, synthesis, and characterization of a beta-sandwich protein.

How an amino acid sequence encodes the information necessary for a protein to adopt a unique tertiary structure remains unresolved. We are addressing this problem by designing "from scratch" protein molecules that will adopt predetermined three-dimensional structures. Based on this strategy, two ide...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Quinn, T P, Tweedy, N B, Williams, R W, Richardson, J S, Richardson, D C
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 1994
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC44683/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8090717/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.91.19.8747
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