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Natural killer (NK) cell profiles in blood and tumour in women with large and locally advanced breast cancer (LLABC) and their contribution to a pathological complete response (PCR) in the tumour following neoadjuvant chemotherapy (NAC): differential restoration of blood profiles by NAC and surgery

BACKGROUND: NK cells contribute to tumour surveillance, inhibition of growth and dissemination by cytotoxicity, secretion of cytokines and interaction with immune cells. Their precise role in human breast cancer is unclear and the effect of therapy poorly studied. The purpose of our study was to cha...

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Bibliografische gegevens
Gepubliceerd in:J Transl Med
Hoofdauteurs: Verma, Chandan, Kaewkangsadan, Viriya, Eremin, Jennifer M, Cowley, Gerard P, Ilyas, Mohammad, El-Sheemy, Mohamed A, Eremin, Oleg
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: BioMed Central 2015
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4467635/
https://ncbi.nlm.nih.gov/pubmed/26040463
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12967-015-0535-8
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