Natural killer (NK) cell profiles in blood and tumour in women with large and locally advanced breast cancer (LLABC) and their contribution to a pathological complete response (PCR) in the tumour following neoadjuvant chemotherapy (NAC): differential restoration of blood profiles by NAC and surgery

BACKGROUND: NK cells contribute to tumour surveillance, inhibition of growth and dissemination by cytotoxicity, secretion of cytokines and interaction with immune cells. Their precise role in human breast cancer is unclear and the effect of therapy poorly studied. The purpose of our study was to cha...

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Detalhes bibliográficos
Publicado no:J Transl Med
Main Authors: Verma, Chandan, Kaewkangsadan, Viriya, Eremin, Jennifer M, Cowley, Gerard P, Ilyas, Mohammad, El-Sheemy, Mohamed A, Eremin, Oleg
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2015
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4467635/
https://ncbi.nlm.nih.gov/pubmed/26040463
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12967-015-0535-8
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