Monocyte Tumor Necrosis Factor-α–Converting Enzyme Catalytic Activity and Substrate Shedding in Sepsis and Noninfectious Systemic Inflammation*

OBJECTIVES: To determine the effect of severe sepsis on monocyte tumor necrosis factor-α–converting enzyme baseline and inducible activity profiles. DESIGN: Observational clinical study. SETTING: Mixed surgical/medical teaching hospital ICU. PATIENTS: Sixteen patients with severe sepsis, 15 healthy...

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Detalhes bibliográficos
Publicado no:Crit Care Med
Main Authors: O’Callaghan, David J. P., O’Dea, Kieran P., Scott, Alasdair J., Takata, Masao, Gordon, Anthony C.
Formato: Artigo
Idioma:Inglês
Publicado em: Lippincott Williams & Wilkins 2015
Assuntos:
Feature Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4467590/
https://ncbi.nlm.nih.gov/pubmed/25867908
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/CCM.0000000000000992
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