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Optimal Tumor Necrosis Factor Induction by Plasmodium falciparum Requires the Highly Localized Release of Parasite Products

Overproduction of tumor necrosis factor (TNF) has been linked with the pathogenesis of Plasmodium falciparum malaria. Here, we examined why the high levels of TNF-inducing activity associated with P. falciparum-parasitized erythrocytes (PE) appear to be lost after cell lysis. Static coculture of PE...

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Autores principales: O'Dea, Kieran P., Pasvol, Geoffrey
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2003
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC155712/
https://ncbi.nlm.nih.gov/pubmed/12761094
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.71.6.3155-3164.2003
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