Optimal Tumor Necrosis Factor Induction by Plasmodium falciparum Requires the Highly Localized Release of Parasite Products

Overproduction of tumor necrosis factor (TNF) has been linked with the pathogenesis of Plasmodium falciparum malaria. Here, we examined why the high levels of TNF-inducing activity associated with P. falciparum-parasitized erythrocytes (PE) appear to be lost after cell lysis. Static coculture of PE...

Full description

Saved in:
Bibliographic Details
Main Authors: O'Dea, Kieran P., Pasvol, Geoffrey
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2003
Subjects:
Fungal and Parasitic Infections
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC155712/
https://ncbi.nlm.nih.gov/pubmed/12761094
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.71.6.3155-3164.2003
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items