Optimal Tumor Necrosis Factor Induction by Plasmodium falciparum Requires the Highly Localized Release of Parasite Products

Overproduction of tumor necrosis factor (TNF) has been linked with the pathogenesis of Plasmodium falciparum malaria. Here, we examined why the high levels of TNF-inducing activity associated with P. falciparum-parasitized erythrocytes (PE) appear to be lost after cell lysis. Static coculture of PE...

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Detalhes bibliográficos

Publicado no:	Infect Immun
Principais autores:	O'Dea, Kieran P., Pasvol, Geoffrey
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 2003
Assuntos:	Fungal and Parasitic Infections
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC155712/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12761094/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/IAI.71.6.3155-3164.2003
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