Optimal Tumor Necrosis Factor Induction by Plasmodium falciparum Requires the Highly Localized Release of Parasite Products

Overproduction of tumor necrosis factor (TNF) has been linked with the pathogenesis of Plasmodium falciparum malaria. Here, we examined why the high levels of TNF-inducing activity associated with P. falciparum-parasitized erythrocytes (PE) appear to be lost after cell lysis. Static coculture of PE...

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Pubblicato in:	Infect Immun
Autori principali:	O'Dea, Kieran P., Pasvol, Geoffrey
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Microbiology (ASM) 2003
Soggetti:	Fungal and Parasitic Infections
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC155712/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12761094/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/IAI.71.6.3155-3164.2003
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