BNP DELETION LEADS TO PROGRESSIVE HYPERTENSION, ASSOCIATED ORGAN DAMAGE, AND REDUCED SURVIVAL: A NOVEL MODEL FOR HUMAN HYPERTENSION

Altered myocardial structure and function, secondary to chronically elevated blood pressure, are leading causes of heart failure and death. B-type natriuretic peptide, a guanylyl cyclase A agonist, is a cardiac hormone integral to cardiovascular regulation. Studies have demonstrated a causal relatio...

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Detalhes bibliográficos
Publicado no:Hypertension
Main Authors: Holditch, Sara J., Schreiber, Claire A., Nini, Ryan, Tonne, Jason M., Peng, Kah-Whye, Geurts, Aron, Jacob, Howard J., Burnett, John C., Cataliotti, Alessandro, Ikeda, Yasuhiro
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4467451/
https://ncbi.nlm.nih.gov/pubmed/26063669
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/HYPERTENSIONAHA.115.05610
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