Identification of vitamin B1 metabolism as a tumor-specific radiosensitizing pathway using a high-throughput colony formation screen

Colony formation is the gold standard assay for determining reproductive cell death after radiation treatment, since effects on proliferation often do not reflect survival. We have developed a high-throughput radiosensitivity screening method based on clonogenicity and screened a siRNA library again...

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Udgivet i:Oncotarget
Main Authors: Tiwana, Gaganpreet S., Prevo, Remko, Buffa, Francesca M., Yu, Sheng, Ebner, Daniel V., Howarth, Alison, Folkes, Lisa K., Budwal, Balam, Chu, Kwun-Ye, Durrant, Lisa, Muschel, Ruth J., McKenna, W. Gillies, Higgins, Geoff S.
Format: Artigo
Sprog:Inglês
Udgivet: Impact Journals LLC 2015
Fag:
Research Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4467415/
https://ncbi.nlm.nih.gov/pubmed/25788274
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