Cell-specific expression of artificial microRNAs targeting essential genes exhibit potent antitumor effect on hepatocellular carcinoma cells

To achieve specific and potent antitumor effect of hepatocyte carcinoma cells, replication defective adenoviral vectors, namely rAd/AFP-amiRG, rAd/AFP-amiRE and rAd/AFP-amiRP, were constructed which were armed with artificial microRNAs (amiRs) targeting essential functional genes glyceraldehyde-3-ph...

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Dades bibliogràfiques
Publicat a:Oncotarget
Autors principals: Mao, Chenyu, Liu, Hao, Chen, Ping, Ye, Jingjia, Teng, Lisong, Jia, Zhenyu, Cao, Jiang
Format: Artigo
Idioma:Inglês
Publicat: Impact Journals LLC 2015
Matèries:
Research Paper
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4467396/
https://ncbi.nlm.nih.gov/pubmed/25691059
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