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Cell-specific expression of artificial microRNAs targeting essential genes exhibit potent antitumor effect on hepatocellular carcinoma cells

To achieve specific and potent antitumor effect of hepatocyte carcinoma cells, replication defective adenoviral vectors, namely rAd/AFP-amiRG, rAd/AFP-amiRE and rAd/AFP-amiRP, were constructed which were armed with artificial microRNAs (amiRs) targeting essential functional genes glyceraldehyde-3-ph...

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Bibliografski detalji
Izdano u:Oncotarget
Glavni autori: Mao, Chenyu, Liu, Hao, Chen, Ping, Ye, Jingjia, Teng, Lisong, Jia, Zhenyu, Cao, Jiang
Format: Artigo
Jezik:Inglês
Izdano: Impact Journals LLC 2015
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Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4467396/
https://ncbi.nlm.nih.gov/pubmed/25691059
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