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Aberrant nuclear factor-kappa B activity in acute myeloid Leukemia: from molecular pathogenesis to therapeutic target

The overall survival of patients with acute myeloid leukemia (AML) has not been improved significantly over the last decade. Molecularly targeted agents hold promise to change the therapeutic landscape in AML. The nuclear factor kappa B (NF-κB) controls a plethora of biological process through switc...

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Publicat a:Oncotarget
Autors principals: Zhou, Jianbiao, Ching, Ying Qing, Chng, Wee-Joo
Format: Artigo
Idioma:Inglês
Publicat: Impact Journals LLC 2015
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4467382/
https://ncbi.nlm.nih.gov/pubmed/25823927
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