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Cis-regulatory somatic mutations and gene-expression alteration in B-cell lymphomas

BACKGROUND: With the rapid increase of whole-genome sequencing of human cancers, an important opportunity to analyze and characterize somatic mutations lying within cis-regulatory regions has emerged. A focus on protein-coding regions to identify nonsense or missense mutations disruptive to protein...

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Detalhes bibliográficos
Publicado no:Genome Biol
Main Authors: Mathelier, Anthony, Lefebvre, Calvin, Zhang, Allen W, Arenillas, David J, Ding, Jiarui, Wasserman, Wyeth W, Shah, Sohrab P
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4467049/
https://ncbi.nlm.nih.gov/pubmed/25903198
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13059-015-0648-7
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