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Aggravation of post-ischemic liver injury by overexpression of insulin-like growth factor binding protein 3

Insulin-like growth factor-1 (IGF-1) is known to inhibit reperfusion-induced apoptosis. IGF-binding protein-3 (IGFBP-3) is the major circulating carrier protein for IGF-1 and induces apoptosis. In this study, we determined if IGFBP-3 was important in the hepatic response to I/R. To deliver IGFBP-3,...

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Detalles Bibliográficos
Publicado en:Sci Rep
Main Authors: Zhou, Lu, Koh, Hyoung-Won, Bae, Ui-Jin, Park, Byung-Hyun
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group 2015
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4466889/
https://ncbi.nlm.nih.gov/pubmed/26073647
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep11231
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