Transcription factor PRDM8 is required for rod bipolar and type 2 OFF-cone bipolar cell survival and amacrine subtype identity

Retinal bipolar (BP) cells mediate the earliest steps in image processing in the visual system, but the genetic pathways that regulate their development and function are incompletely known. We identified PRDI-BF1 and RIZ homology domain containing 8 (PRDM8) as a highly conserved transcription factor...

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Publicado en:Proc Natl Acad Sci U S A
Autores principales: Jung, Cynthia C., Atan, Denize, Ng, David, Ploder, Lynda, Ross, Sarah E., Klein, Martin, Birch, David G., Diez, Eduardo, McInnes, Roderick R.
Formato: Artigo
Lenguaje:Inglês
Publicado: National Academy of Sciences 2015
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PNAS Plus
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4466745/
https://ncbi.nlm.nih.gov/pubmed/26023183
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1505870112
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