Transcription factor PRDM8 is required for rod bipolar and type 2 OFF-cone bipolar cell survival and amacrine subtype identity

Retinal bipolar (BP) cells mediate the earliest steps in image processing in the visual system, but the genetic pathways that regulate their development and function are incompletely known. We identified PRDI-BF1 and RIZ homology domain containing 8 (PRDM8) as a highly conserved transcription factor...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Proc Natl Acad Sci U S A
Main Authors: Jung, Cynthia C., Atan, Denize, Ng, David, Ploder, Lynda, Ross, Sarah E., Klein, Martin, Birch, David G., Diez, Eduardo, McInnes, Roderick R.
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2015
Teme:
PNAS Plus
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4466745/
https://ncbi.nlm.nih.gov/pubmed/26023183
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1505870112
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