Human ortholog of Drosophila Melted impedes SMAD2 release from TGF-β receptor I to inhibit TGF-β signaling

Drosophila melted encodes a pleckstrin homology (PH) domain-containing protein that enables normal tissue growth, metabolism, and photoreceptor differentiation by modulating Forkhead box O (FOXO), target of rapamycin, and Hippo signaling pathways. Ventricular zone expressed PH domain-containing 1 (V...

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Publicat a:Proc Natl Acad Sci U S A
Autors principals: Shathasivam, Premalatha, Kollara, Alexandra, Ringuette, Maurice J., Virtanen, Carl, Wrana, Jeffrey L., Brown, Theodore J.
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2015
Matèries:
PNAS Plus
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4466715/
https://ncbi.nlm.nih.gov/pubmed/26039994
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1504671112
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