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H4K12ac is regulated by estrogen receptor-alpha and is associated with BRD4 function and inducible transcription

Hormone-dependent gene expression requires dynamic and coordinated epigenetic changes. Estrogen receptor-positive (ER(+)) breast cancer is particularly dependent upon extensive chromatin remodeling and changes in histone modifications for the induction of hormone-responsive gene expression. Our prev...

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Bibliografiske detaljer
Udgivet i:Oncotarget
Main Authors: Nagarajan, Sankari, Benito, Eva, Fischer, Andre, Johnsen, Steven A.
Format: Artigo
Sprog:Inglês
Udgivet: Impact Journals LLC 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4466686/
https://ncbi.nlm.nih.gov/pubmed/25788266
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