Cytokeratin 5/6 fingerprinting in HER2-positive tumors identifies a poor prognosis and trastuzumab-resistant Basal-HER2 subtype of breast cancer

There is an urgent need to refine the prognostic taxonomy of HER2+ breast carcinomas and develop easy-to-use, clinic-based prediction algorithms to distinguish between good- and poor-responders to trastuzumab-based therapy. Building on earlier studies suggesting that HER2+ tumors enriched with molec...

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Dettagli Bibliografici
Pubblicato in:Oncotarget
Autori principali: Martin-Castillo, Begoña, Lopez-Bonet, Eugeni, Buxó, Maria, Dorca, Joan, Tuca-Rodríguez, Francesc, Ruano, Miguel Alonso, Colomer, Ramon, Menendez, Javier A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Impact Journals LLC 2015
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Research Paper
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4466672/
https://ncbi.nlm.nih.gov/pubmed/25742793
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