P-selectin-mediated platelet adhesion promotes tumor growth

Blood platelets foster carcinogenesis. We found that platelets are accumulated in human tumors. P-selectin deficiency and soluble P-selectin abolish platelet deposition within tumors, decreasing secretion of vascular endothelial growth factor and angiogenesis, thereby suppressing tumor growth. Bindi...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Qi, Cuiling, Wei, Bo, Zhou, Weijie, Yang, Yang, Li, Bin, Guo, Simei, Li, Jialin, Ye, Jie, Li, Jiangchao, Zhang, Qianqian, Lan, Tian, He, Xiaodong, Cao, Liu, Zhou, Jia, Geng, Jianguo, Wang, Lijing
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2015
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4466636/
https://ncbi.nlm.nih.gov/pubmed/25762641
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