Glipizide suppresses prostate cancer progression in the TRAMP model by inhibiting angiogenesis

Drug repurposing of non-cancer drugs represents an attractive approach to develop new cancer therapy. Using the TRAMP transgenic mouse model, glipizide, a widely used drug for type 2 diabetes mellitus, has been identified to suppress prostate cancer (PC) growth and metastasis. Angiogenesis is intima...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Qi, Cuiling, Bin Li, Yang, Yang, Yang, Yongxia, Li, Jialin, Zhou, Qin, Wen, Yinxin, Zeng, Cuiling, Zheng, Lingyun, Zhang, Qianqian, Li, Jiangchao, He, Xiaodong, Zhou, Jia, Shao, Chunkui, Wang, Lijing
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4904209/
https://ncbi.nlm.nih.gov/pubmed/27292155
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep27819
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