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Invariant Natural Killer T Cells Play a Role in Chemotaxis, Complement Activation and Mucus Production in a Mouse Model of Airway Hyperreactivity and Inflammation

CD1d-restricted invariant natural killer T (iNKT) cells play a critical role in the induction of airway hyperreactivity (AHR). After intranasal alpha-galactosylceramide (α-GalCer) administration, bronchoalveolar lavage fluid (BALF) proteins from mouse lung were resolved by two-dimensional differenti...

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Veröffentlicht in:PLoS One
Hauptverfasser: Karisola, Piia, Lehto, Maili, Kinaret, Pia, Ahonen, Niina, Haapakoski, Rita, Anthoni, Minna, Taniguchi, Masaru, Wolff, Henrik, Puustinen, Anne, Alenius, Harri
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2015
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4466557/
https://ncbi.nlm.nih.gov/pubmed/26067998
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0129446
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