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Smad3 -signalling and Th2 cytokines in normal mouse airways and in a mouse model of asthma

This study investigates the role of Smad3 signalling for the T-helper2 (Th2) cytokine homeostasis in normal lungs and in a mouse model of asthma. We used mice deficient for Smad3, a central part of the major signal transduction pathway for TGF-β and other related cytokines, and a mouse model for all...

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Bibliografiske detaljer
Main Authors: Anthoni, Minna, Wang, Guoying, Leino, Marina S., Lauerma, Antti I., Alenius, Harri T., Wolff, Henrik J.
Format: Artigo
Sprog:Inglês
Udgivet: Ivyspring International Publisher 2007
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2096738/
https://ncbi.nlm.nih.gov/pubmed/18071588
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